The word "handicap" is often used interchangeably with "disability" However, the two words do not have the same meaning.
Disability is a condition caused by an accident, trauma, genetics, or disease which may limit a person's mobility, vision, speech, or cognitive function.
Handicap is a physical or attitudinal constraint that is imposed upon a person, regardless of whether that person has a disability.
Example: Some people with disabilities use wheelchairs. Stairs, narrow doorways, and curbs are handicaps imposed upon people with disabilities who use wheelchairs.